The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism

Arvand Haschemi, Paul Kosma, Lars Gille, +16

Cell Metabolism

Drosophila Genome-wide Obesity Screen Reveals Hedgehog as a Determinant of Brown versus White Adipose Cell Fate

J. Andrew Pospisilik, Daniel Schramek, Harald Schnidar, +23

Cell

ObesityMetabolic SyndromeBiologyCell LineageDevelopmental Biology +8

Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression

Monika Linke, Hà Phạm, Karl Katholnig, +19

Nature Immunology

InflammationCell RegulationGranulocyteAutophagyImmunology +10

Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments

Anne Miller, Csörsz Nagy, Bernhard Knapp, +7

Cell Metabolism

Metabolic NetworkMetabolic ConfigurationsBioenergeticsMedicineSingle-cell Biology +7

Hepatic miR-144 Drives Fumarase Activity Preventing NRF2 Activation During Obesity

Valerio Azzimato, Ping Chen, Emelie Barreby, +20

Gastroenterology

Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A–induced hepatitis

Guido Beldi, Yan Wu, Yara Banz, +8

Hepatology

Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation

Jayne Louise Wilson, Thomas Nägele, Monika Linke, +14

Cell Reports

Human but Not Mouse Adipogenesis Is Critically Dependent on LMO3

Josefine Lindroos, Julia Husa, Gerfried Mitterer, +16

Cell Metabolism

IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcus aureus

Philipp Starkl, Martin L. Watzenboeck, Lauren M. Popov, +15

Immunity

Host ResponseIge Effector MechanismsMast Cell DisorderPathogenesisImmunology +7

Routinely available biomarkers improve prediction of long-term mortality in stable coronary artery disease: the Vienna and Ludwigshafen Coronary Artery Disease (VILCAD) risk score

Georg Goliasch, Marcus E. Kleber, Bernhard Richter, +15

European Heart Journal