Jonathan R. LaRochelle

Early Endosomal Escape of a Cyclic Cell-Penetrating Peptide Allows Effective Cytosolic Cargo Delivery

Ziqing Qian, Jonathan R. LaRochelle, Bisheng Jiang et al. · Biochemistry · 2014 · 172 citations · Full text

Proteinlipid Interaction, Endosomal Escape, Molecular Biology +19

Arginine Topology Controls Escape of Minimally Cationic Proteins from Early Endosomes to the Cytoplasm

Jacob Appelbaum, Jonathan R. LaRochelle, Betsy A. Smith et al. · Chemistry & Biology · 2012 · 168 citations · Full text

Early Endosomes, Cell Organelle, Protein Folding +11

Genetic epidemiology of hereditary tyrosinemia in Quebec and in Saguenay-Lac-St-Jean.

Marc De Braekeleer, Jonathan R. LaRochelle · PubMed · 1990 · 165 citations

Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition

Jonathan R. LaRochelle, Michelle Fodor, Vidyasiri Vemulapalli et al. · Nature Communications · 2018 · 162 citations · Full text

Discovery and Characterization of a Peptide That Enhances Endosomal Escape of Delivered Proteins in Vitro and in Vivo

Margie Li, Yong Tao, Yilai Shu et al. · Journal of the American Chemical Society · 2015 · 132 citations · Full text

Protein Secretion, Peptide Engineering, Endosomal Escape +20