Concepedia

David A. Born

DA

9

Publications

1.1K

Citations

9

H-Index

2015

Active since

Affiliations

Beam Therapeutics (United States)(Current)

Massachusetts Institute of Technology

Harvard University

Howard Hughes Medical Institute

David A. Born is an author at Beam Therapeutics (United States) specializing in medicine, medicinal chemistry, and drug discovery.

ORCID

Top concepts

Publications per year

2015–2021

9

Publications

9

Directed evolution of adenine base editors with increased activity and therapeutic application

Nicole M. Gaudelli, Dieter K. Lam, Holly A. Rees et al. · Nature Biotechnology · 2020 · 505 citations

, , +10

Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity

Yi Yu, Thomas Leete, David A. Born et al. · Nature Communications · 2020 · 182 citations · Full text

Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects

Phuong A. Nguyen, David A. Born, Aimée M. Deaton et al. · Nature Communications · 2019 · 101 citations · Full text

Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation

S. Haihua Chu, Michael S. Packer, Holly A. Rees et al. · The CRISPR Journal · 2021 · 82 citations

, , +19

Structural basis for methylphosphonate biosynthesis

David A. Born, Emily C. Ulrich, Kou‐San Ju et al. · Science · 2017 · 59 citations · Full text

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