Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apétoh, François Ghiringhelli, Antoine Tesnière, +25

Nature Medicine

InflammationToll-like ReceptorsCancer ImmunosurveillanceImmune Cell DevelopmentInnate Immune System +10

DNA Repair by ERCC1 in Non–Small-Cell Lung Cancer and Cisplatin-Based Adjuvant Chemotherapy

Ken A. Olaussen, Ariane Dunant, Pierre Fouret, +13

New England Journal of Medicine

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

Joseph Wolfers, Anne Lozier, Graça Raposo, +10

Nature Medicine

Ctl Cross-primingTumor ImmunologyCancer ImmunosurveillanceTumor-derived ExosomesExosomes +12

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

Bernard Escudier, Thierry Dorval, Nathalie Chaput, +21

Journal of Translational Medicine

Dendritic cells directly trigger NK cell functions: Cross-talk relevant in innate anti-tumor immune responses in vivo

Nadine Fernandez, Anne Lozier, Caroline Flament, +7

Nature Medicine

Cancer ImmunosurveillanceNk Cell FunctionsInnate Immune SystemImmunologyTumor Immunity +10

Recombinant Human Interleukin-2, Recombinant Human Interferon Alfa-2a, or Both in Metastatic Renal-Cell Carcinoma

Sylvie Négrier, Bernard Escudier, Christine Lasset, +9

New England Journal of Medicine

Malignant effusions and immunogenic tumour-derived exosomes

Fabrice André, Noël E.C. Schartz, Mojgan Movassagh, +12

The Lancet

ExosomesPathologyExtracellular MicrovesiclesMedicineMalignant Disease +2

CD4<b>+</b>CD25<b>+</b> regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

François Ghiringhelli, Cédric Menard, Magali Terme, +18

The Journal of Experimental Medicine

Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells

Fabrice André, Nathalie Chaput, Noël E.C. Schartz, +11

The Journal of Immunology

ImmunologyCurrent Immunization ProtocolsImmunodominanceAntigen ProcessingImmune Cell Therapy +18

Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

Véronique Winnepenninckx, Vladimir Lazar, Stefan Michiels, +13

JNCI Journal of the National Cancer Institute