Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Bertrand Routy, Emmanuelle Le Chatelier, Lisa Derosa, +45

Science

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

Marie Vétizou, Jonathan M. Pitt, Romain Daillère, +35

Science

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell derived exosomes

Laurence Zitvogel, Armelle Régnault, Anne Lozier, +6

Nature Medicine

VaccinationNovel Cell-free VaccineDendritic CellImmunologyTherapeutic Vaccine +7

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

Joseph Wolfers, Anne Lozier, Graça Raposo, +10

Nature Medicine

Ctl Cross-primingTumor ImmunologyCancer ImmunosurveillanceTumor-derived ExosomesExosomes +12

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

Bernard Escudier, Thierry Dorval, Nathalie Chaput, +21

Journal of Translational Medicine

Dendritic cells directly trigger NK cell functions: Cross-talk relevant in innate anti-tumor immune responses in vivo

Nadine Fernandez, Anne Lozier, Caroline Flament, +7

Nature Medicine

Cancer ImmunosurveillanceNk Cell FunctionsInnate Immune SystemImmunologyTumor Immunity +10

Malignant effusions and immunogenic tumour-derived exosomes

Fabrice André, Noël E.C. Schartz, Mojgan Movassagh, +12

The Lancet

ExosomesPathologyExtracellular MicrovesiclesMedicineMalignant Disease +2

CD4<b>+</b>CD25<b>+</b> regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner

François Ghiringhelli, Cédric Menard, Magali Terme, +18

The Journal of Experimental Medicine

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

Romain Daillère, Marie Vétizou, Nadine Waldschmitt, +33

Immunity

Health SciencesMucosal ImmunologyPathogenesisImmunologyEnterococcus Hirae +7

Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells

Fabrice André, Nathalie Chaput, Noël E.C. Schartz, +11

The Journal of Immunology

ImmunologyCurrent Immunization ProtocolsImmunodominanceAntigen ProcessingImmune Cell Therapy +18