Martin Frotscher

Design, Synthesis, Biological Evaluation and Pharmacokinetics of Bis(hydroxyphenyl) substituted Azoles, Thiophenes, Benzenes, and Aza-Benzenes as Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1)

Emmanuel Bey, Sandrine Marchais‐Oberwinkler, Ruth Werth et al. · Journal of Medicinal Chemistry · 2008 · 107 citations · Full text

Design, Synthesis, and Biological Evaluation of (Hydroxyphenyl)naphthalene and -quinoline Derivatives: Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) for the Treatment of Estrogen-Dependent Diseases

Martin Frotscher, Erika Ziegler, Sandrine Marchais‐Oberwinkler et al. · Journal of Medicinal Chemistry · 2008 · 86 citations · Full text

Potent Estradiol, Pharmacotherapy, Pharmaceutical Chemistry +17

New Insights into the SAR and Binding Modes of Bis(hydroxyphenyl)thiophenes and -benzenes: Influence of Additional Substituents on 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Inhibitory Activity and Selectivity

Emmanuel Bey, Sandrine Marchais‐Oberwinkler, Matthias Negri et al. · Journal of Medicinal Chemistry · 2009 · 75 citations · Full text

Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) for the treatment of estrogen-dependent diseases

Emmanuel Bey, Sandrine Marchais‐Oberwinkler, Patricia Kruchten et al. · Bioorganic & Medicinal Chemistry · 2008 · 65 citations · Full text

Medicinal Chemistry, Estrogen-dependent Diseases, Biochemistry +11

Substituted 6-Phenyl-2-naphthols. Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1): Design, Synthesis, Biological Evaluation, and Pharmacokinetics

Sandrine Marchais‐Oberwinkler, Patricia Kruchten, Martin Frotscher et al. · Journal of Medicinal Chemistry · 2008 · 63 citations · Full text