J. A. Lowden

Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease.

Robert G. Korneluk, Don J. Mahuran, Kuldeep Neote et al. · Journal of Biological Chemistry · 1986 · 177 citations · Full text

THE ISOLATION AND CHARACTERIZATION OF AN ACID-SOLUBLE PROTEIN FROM MYELIN

J. A. Lowden, M.A. Moscarello, Rachel Morecki · Canadian Journal of Biochemistry · 1966 · 144 citations

Lipid Analysis, Proteinlipid Interaction, Food Biophysics +19

Identification of an altered splice site in Ashkenazi Tay-Sachs disease

Enrico Arpaia, Anne Dumbrille-Ross, Thomas Maler et al. · Nature · 1988 · 142 citations

Genetics, Pathogenesis, Pathology +5

Isolation of cDNA clones coding for the beta subunit of human beta-hexosaminidase.

Brian F. O’Dowd, F Quan, H.F. Willard et al. · Proceedings of the National Academy of Sciences · 1985 · 116 citations · Full text

Genetics, Glycobiology, Molecular Biology +21

The subunit and polypeptide structure of hexosaminidases from human placenta

Don J. Mahuran, J. A. Lowden · Canadian Journal of Biochemistry · 1980 · 114 citations

Protein Assembly, Molecular Biology, Molecular Genetics +18