Evidence for osteocyte regulation of bone homeostasis through RANKL expression

Tomoki Nakashima, Mikihito Hayashi, Takanobu Fukunaga, +9

Nature Medicine

Orthopaedic SurgeryBone Morphogenic ProteinBone RemodelingOsteoarthritisOsteoporosis +6

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis

Noriko Komatsu, Kazuo Okamoto, Shinichiro Sawa, +6

Nature Medicine

InflammationRheumatologyAutoimmune DiseaseAllergyPathogenic Conversion +9

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

Masatsugu Oh‐hora, Megumi Yamashita, Patrick G. Hogan, +6

Nature Immunology

T Cell ActivationMolecular PhysiologySignal TransductionMedicineMolecular Biology +7

Biochemical and Functional Characterization of Orai Proteins

Yousang Gwack, Sonal Srikanth, Stefan Feske, +5

Journal of Biological Chemistry

Molecular RegulationCellular PhysiologyTranscriptional RegulationTranscription Factor NfatOrai Proteins +18

Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1

Yousang Gwack, Sonal Srikanth, Masatsugu Oh‐hora, +10

Molecular and Cellular Biology

ImmunologyImmunologic MechanismCellular PhysiologyOrai1 GeneInflammation +17

Essential role for ERK2 mitogen‐activated protein kinase in placental development

Naoya Hatano, Yoshiko Mori, Masatsugu Oh‐hora, +7

Genes to Cells

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria

Akiko Yonekawa, Shinobu Saijo, Yoshihiko Hoshino, +9

Immunity

Medical MicrobiologyHealth SciencesBiochemistryBacteriologyMolecular Biology +8

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

Kazuo Okamoto, Yoshiko Iwai, Masatsugu Oh‐hora, +8

Nature

Th17 DevelopmentTranscriptional RegulationSignal TransductionSignaling PathwayCell Regulation +4

STIM1 gates the store-operated calcium channel ORAI1 in vitro

Yubin Zhou, Paul Meraner, Hyoung T. Kwon, +7

Nature Structural & Molecular Biology

Signal TransductionMolecular PhysiologyPhysiologyElectrophysiologyCellular Biochemistry +4

Dynamic Movement of the Calcium Sensor STIM1 and the Calcium Channel Orai1 in Activated T-Cells: Puncta and Distal Caps

Valarie A. Barr, Kelsie M. Bernot, Sonal Srikanth, +8

Molecular Biology of the Cell

Molecular BiologyCytoskeletonMechanotransductionCellular PhysiologyProteins Stim1 +22