Patrick G. Hogan

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Stefan Feske, Yousang Gwack, Murali Prakriya et al. · Nature · 2006 · 2.3K citations

Life Sciences, Immunology, Molecular Biology +10

Orai1 is an essential pore subunit of the CRAC channel

Murali Prakriya, Stefan Feske, Yousang Gwack et al. · Nature · 2006 · 1.3K citations

Natural Sciences, Biochemistry, Molecular Biology +13

The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells

Gustavo Martínez, Renata M. Pereira, Tarmo Äijö et al. · Immunity · 2015 · 856 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8 ⁺ T cell exhaustion

Hyungseok Seo, Joyce Chen, Edahí González‐Avalos et al. · Proceedings of the National Academy of Sciences · 2019 · 769 citations · Full text

Life Sciences, Immunology, Oncology +17

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

Masatsugu Oh‐hora, Megumi Yamashita, Patrick G. Hogan et al. · Nature Immunology · 2008 · 587 citations

Life Sciences, Immunology, Molecular Biology +16