Carmine Fedele

PD-L1 engagement on T cells promotes self-tolerance and suppression of neighboring macrophages and effector T cells in cancer

Brian Diskin, Salma Adam, Marcelo Ferreira Cassini et al. · Nature Immunology · 2020 · 381 citations

Cancer Immunosurveillance, T Cells, Pd-l1 Engagement +10

SHP2 Inhibition Prevents Adaptive Resistance to MEK Inhibitors in Multiple Cancer Models

Carmine Fedele, Hao Ran, Brian Diskin et al. · Cancer Discovery · 2018 · 305 citations · Full text

SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling

Carmine Fedele, Shuai Li, Kai Wen Teng et al. · The Journal of Experimental Medicine · 2020 · 242 citations · Full text

Immunology, Cancer Biology, Tumor Biology +16

The αvβ6 Integrin Is Transferred Intercellularly via Exosomes

Carmine Fedele, Amrita Singh, Brad J. Zerlanko et al. · Journal of Biological Chemistry · 2015 · 167 citations · Full text

Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype

Amrita Singh, Carmine Fedele, Huimin Lu et al. · Molecular Cancer Research · 2016 · 153 citations · Full text