Wayne Harshbarger

Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib

Wayne Harshbarger, C. S. Miller, Chandler Diedrich et al. · Structure · 2015 · 163 citations

Life Sciences, Biochemistry, Molecular Biology +14

Discovery of a selective inhibitor of doublecortin like kinase 1

Fleur M. Ferguson, Behnam Nabet, Srivatsan Raghavan et al. · Nature Chemical Biology · 2020 · 114 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine

Wayne Harshbarger, Sudershan Reddy Gondi, Scott B. Ficarro et al. · Journal of Biological Chemistry · 2016 · 87 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

Yan Liu, Fleur M. Ferguson, Lianbo Li et al. · Cell chemical biology · 2020 · 22 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +13

Synthesis and Structure–Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6<i>H</i>-benzo[<i>e</i>]pyrimido[5,4-<i>b</i>][1,4]diazepin-6-one Scaffold

Fleur M. Ferguson, Yan Liu, Wayne Harshbarger et al. · Journal of Medicinal Chemistry · 2020 · 21 citations · Full text

Medicine, Medicinal Chemistry, Oncology +11