Tsuyoshi Hirota

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

Eric Erquan Zhang, Yi Liu, Renaud Dentin et al. · Nature Medicine · 2010 · 548 citations · Full text

Energy Homeostasis, Signal Transduction, Camp Signaling +11

Identification of Small Molecule Activators of Cryptochrome

Tsuyoshi Hirota, Jae Wook Lee, Peter C. St. John et al. · Science · 2012 · 494 citations · Full text

Molecular Biology, Cryptochrome, Circadian Clock +17

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

Eric Erquan Zhang, Andrew C. Liu, Tsuyoshi Hirota et al. · Cell · 2009 · 430 citations · Full text

Chromatin, Functional Genomics, Human Cells +10

Glucose Down-regulates Per1 and Per2mRNA Levels and Induces Circadian Gene Expression in Cultured Rat-1 Fibroblasts

Tsuyoshi Hirota, Toshiyuki Okano, Koichi Kokame et al. · Journal of Biological Chemistry · 2002 · 308 citations · Full text

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β

Tsuyoshi Hirota, Warren G. Lewis, Andrew C. Liu et al. · Proceedings of the National Academy of Sciences · 2008 · 285 citations · Full text