Philip R. Kym

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

Barbara L. Cool, Bradley A. Zinker, William J. Chiou et al. · Cell Metabolism · 2006 · 918 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

Jun Chen, Shailen K. Joshi, Stanley DiDomenico et al. · Pain · 2011 · 271 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

A Novel Antiinflammatory Maintains Glucocorticoid Efficacy with Reduced Side Effects

Michael J. Coghlan, Peer B. Jacobson, Ben Lane et al. · Molecular Endocrinology · 2003 · 221 citations

Life Sciences, Pharmacology, Pharmacotherapy +17

TRPA1 Modulation of Spontaneous and Mechanically Evoked Firing of Spinal Neurons in Uninjured, Osteoarthritic, and Inflamed Rats

Steve McGaraughty, Katharine L. Chu, Richard J. Perner et al. · Molecular Pain · 2010 · 194 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity

Christina K. Baumgartner, Hakimeh Ebrahimi-Nik, Arvin Iracheta‐Vellve et al. · Nature · 2023 · 174 citations · Full text

Life Sciences, Immunology, Pharmacology +17