Kristen W. Lynch

A compendium of RNA-binding motifs for decoding gene regulation

Debashish Ray, Hilal Kazan, Kate B. Cook et al. · Nature · 2013 · 1.6K citations

Sequence Motif, Natural Sciences, Rna Binding Proteins +7

Convergence of Acquired Mutations and Alternative Splicing of <i>CD19</i> Enables Resistance to CART-19 Immunotherapy

Elena Sotillo, David M. Barrett, Kathryn L. Black et al. · Cancer Discovery · 2015 · 1.2K citations · Full text

A new view of transcriptome complexity and regulation through the lens of local splicing variations

Jorge Vaquero-Garcia, Alejandro Barrera, Matthew R. Gazzara et al. · eLife · 2016 · 511 citations · Full text

Transcriptome Complexity, Genetics, Rna Splicing +27

An optogenetic gene expression system with rapid activation and deactivation kinetics

Laura B. Motta-Mena, Anna Reade, Michael J. Mallory et al. · Nature Chemical Biology · 2014 · 386 citations · Full text

Rapid Activation, Transcriptional Regulation, Protein Expression +10

Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.

Kristen W. Lynch, Tom Maniatis · Genes & Development · 1996 · 235 citations · Full text

Sr Family, Genetics, Rna Splicing +17