Bernadette Bertin

Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies

Fabrice Vergne, Patrick Bernardelli, Edwige Lorthiois et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1

Edwige Lorthiois, Patrick Bernardelli, Fabrice Vergne et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Synthesis, Structure−Activity Relationships, and Pharmacological Profile of 9-Amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-<i>h</i><i>i</i>]indoles:  Discovery of Potent, Selective Phosphodiesterase Type 4 Inhibitors

Catherine Burnouf, Eric Auclair, Nadine Avenel et al. · Journal of Medicinal Chemistry · 2000 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives

Patrick Bernardelli, Edwige Lorthiois, Fabrice Vergne et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthesis and structure–activity relationships of 4-oxo-1-phenyl-3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indoles: novel PDE4 inhibitors

Yves Pascal, Charles R. Andrianjara, Eric Auclair et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14