Concepedia

Lachlan Clydesdale

LC

Statistics

Publications

6

Citations

737

H-Index

6

Active since

2017

Affiliations

Monash University(Current)

Fudan University

National Center for Drug Screening

Shanghai Institute of Materia Medica

University of Essex

Lachlan Clydesdale is an author at Monash University specializing in molecular physiology, signal transduction, and cell signaling.

Top concepts

Publications per year

2017–2022

6

Publications

6

Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex

Yi-Lynn Liang, Maryam Khoshouei, Alisa Glukhova et al. · Nature · 2018 · 325 citations · Full text

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Activation of the GLP-1 receptor by a non-peptidic agonist

Peishen Zhao, Yi-Lynn Liang, Matthew J. Belousoff et al. · Nature · 2020 · 167 citations · Full text

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Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation

Giuseppe Deganutti, Yi-Lynn Liang, Xin Zhang et al. · Nature Communications · 2022 · 76 citations · Full text

Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1

Marlies V. Hager, Lachlan Clydesdale, Samuel H. Gellman et al. · Biochemical Pharmacology · 2017 · 58 citations · Full text

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Glucagon-like peptide-1 receptor internalisation controls spatiotemporal signalling mediated by biased agonists

Madeleine M. Fletcher, Michelle L. Halls, Peishen Zhao et al. · Biochemical Pharmacology · 2018 · 57 citations

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