Giuseppe Deganutti - Concepedia

Author

Giuseppe Deganutti

University of Essex ORCID

Also Known As

Deganutti, Giuseppe, Giuseppe Deganutti, Ludovico Pipitò

112

Publications

1.8K

Citations

H-Index

Concepts

All Affiliations

University of Essex Monash University Coventry University University of Padua The University of Tokyo

About

Giuseppe Deganutti is an author at University of Essex specializing in medicine, molecular biology, and signal transduction.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	764
2	Engineering	4	4	212
3	Natural Sciences	4	4	126
4	Biochemistry	4	4	131
5	Biomolecular Engineering	1	1	55

Giuseppe Deganutti

Publications

1.5K

Citations

H-Index

Page 1

	Year	Citations
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor Yi-Lynn Liang, Maryam Khoshouei, Giuseppe Deganutti, Nature Signal TransductionMolecular PhysiologySignaling PathwayG Protein-coupled ReceptorMedicine	2018	255
Activation of the GLP-1 receptor by a non-peptidic agonist Peishen Zhao, Yi-Lynn Liang, Matthew J. Belousoff, Nature Molecular PharmacologyMolecular PhysiologySignal TransductionG Protein-coupled ReceptorMedicine	2020	167
Deciphering the Complexity of Ligand–Protein Recognition Pathways Using Supervised Molecular Dynamics (SuMD) Simulations Alberto Cuzzolin, Mattia Sturlese, Giuseppe Deganutti, Journal of Chemical Information and Modeling EngineeringMolecular BiologyMolecular DynamicsMolecular RecognitionMacromolecular Assemblies	2016	98
Structure and Dynamics of Adrenomedullin Receptors AM<sub>1</sub> and AM<sub>2</sub> Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins Yi-Lynn Liang, Matthew J. Belousoff, Madeleine M. Fletcher, ACS Pharmacology & Translational Science	2020	98
Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin Rebekah L. Bower, Lauren R. Yule, Tayla A. Rees, ACS Pharmacology & Translational Science	2018	77
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation Giuseppe Deganutti, Yi-Lynn Liang, Xin Zhang, Nature Communications	2022	76
Structure and dynamics of the active Gs-coupled human secretin receptor Maoqing Dong, Giuseppe Deganutti, Sarah Piper, Nature Communications	2020	68
Supervised molecular dynamics for exploring the druggability of the SARS-CoV-2 spike protein Giuseppe Deganutti, Filippo Prischi, Christopher A. Reynolds Journal of Computer-Aided Molecular Design Drug TargetMedicineBiomolecular AnalysisRational Drug DesignMolecular Biology	2020	61
Understanding allosteric interactions in G protein-coupled receptors using Supervised Molecular Dynamics: A prototype study analysing the human A3 adenosine receptor positive allosteric modulator LUF6000 Giuseppe Deganutti, Alberto Cuzzolin, Antonella Ciancetta, Bioorganic & Medicinal Chemistry Signal TransductionEngineeringG Protein-coupled ReceptorMedicineFunctional Selectivity	2015	55
Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression Mark J. Wall, Emily Hill, Robert Huckstepp, Nature Communications	2022	54

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