Charlene Fallan

Non-bonding 1,5-S⋯O interactions govern chemo- and enantioselectivity in isothiourea-catalyzed annulations of benzazoles

Emily R. T. Robinson, Daniel M. Walden, Charlene Fallan et al. · Chemical Science · 2016 · 156 citations · Full text

Natural Sciences, Chemistry, Catalysis +10

Anhydrides as α,β-unsaturated acyl ammonium precursors: isothiourea-promoted catalytic asymmetric annulation processes

Emily R. T. Robinson, Charlene Fallan, Carmen Simal et al. · Chemical Science · 2013 · 154 citations · Full text

Natural Sciences, Chemistry, Catalysis +8

A C=O⋅⋅⋅Isothiouronium Interaction Dictates Enantiodiscrimination in Acylative Kinetic Resolutions of Tertiary Heterocyclic Alcohols

Mark D. Greenhalgh, Samuel M. Smith, Daniel M. Walden et al. · Angewandte Chemie International Edition · 2018 · 132 citations · Full text

Natural Sciences, Chemistry, Catalysis +15

The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-<i>a</i>]pyridin-6-yl)amino]-9-(tetrahydro-2<i>H</i>-pyran-4-yl)-7,9-dihydro-8<i>H</i>-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor

Frederick W. Goldberg, M. Raymond V. Finlay, Attilla Ting et al. · Journal of Medicinal Chemistry · 2019 · 79 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Stereospecific Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Redox Synthesis of Trifluoromethyl Dihydropyranones and Mechanistic Insights

Alyn T. Davies, James E. Taylor, James J. Douglas et al. · The Journal of Organic Chemistry · 2013 · 70 citations

Natural Sciences, Chemistry, Biocatalysis +11