Puwen Zhang

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1<i>H</i>-indol-5-yl)-1-methyl-1<i>H</i>-pyrrole-2-carbonitrile (WAY-255348)

Andrew Fensome, William R. Adams, Andrea L. Adams et al. · Journal of Medicinal Chemistry · 2008 · 196 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pr Antagonist +13

Potent nonsteroidal progesterone receptor agonists: Synthesis and SAR study of 6-aryl benzoxazines

Puwen Zhang, Eugene A. Terefenko, Andrew Fensome et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 116 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +10

6-Aryl-1,4-dihydro-benzo[<i>d</i>][1,3]oxazin- 2-ones:  A Novel Class of Potent, Selective, and Orally Active Nonsteroidal Progesterone Receptor Antagonists

Puwen Zhang, Eugene A. Terefenko, Andrew Fensome et al. · Journal of Medicinal Chemistry · 2002 · 106 citations · Full text

Synthesis and Structure−Activity Relationship of Novel 6-Aryl-1,4- dihydrobenzo[<i>d</i>][1,3]oxazine-2-thiones as Progesterone Receptor Modulators Leading to the Potent and Selective Nonsteroidal Progesterone Receptor Agonist Tanaproget

Andrew Fensome, Reinhold H. W. Bender, Rajiv Chopra et al. · Journal of Medicinal Chemistry · 2005 · 90 citations · Full text

Hormonal Contraceptive, Oral Contraceptive, Reproductive Health +22

Molecular and Pharmacological Properties of a Potent and Selective Novel Nonsteroidal Progesterone Receptor Agonist Tanaproget

Zhiming Zhang, Andrea Olland, Yuan Zhu et al. · Journal of Biological Chemistry · 2005 · 76 citations · Full text