Herman Borghys

Pharmacokinetics and Disposition of Rilpivirine (TMC278) Nanosuspension as a Long-Acting Injectable Antiretroviral Formulation

Gerben van ‘t Klooster, Eva Hoeben, Herman Borghys et al. · Antimicrobial Agents and Chemotherapy · 2010 · 185 citations · Full text

Pharmaceutical Science, Immunology, Pharmacotherapy +16

Preparation and physicochemical characterization of biodegradable nerve guides containing the nerve growth agent sabeluzole

Geert Verreck, Iksoo Chun, Yufu Li et al. · Biomaterials · 2004 · 88 citations

Tissue Engineering, Physicochemical Characterization, Engineering +7

1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads

Frederik Rombouts, Gary Tresadern, Óscar Delgado et al. · Journal of Medicinal Chemistry · 2015 · 76 citations · Full text

Pharmacotherapy, Hit Generation, Pharmaceutical Chemistry +21

BACE1 Inhibition Induces a Specific Cerebrospinal Fluid β-Amyloid Pattern That Identifies Drug Effects in the Central Nervous System

Niklas Mattsson, Lawrence Rajendran, Henrik Zetterberg et al. · PLoS ONE · 2012 · 70 citations · Full text

Neurochemical Biomarkers, Amyloid Precursor Protein, Synaptic Signaling +20

Acute Effect on the Aβ Isoform Pattern in CSF in Response to γ-Secretase Modulator and Inhibitor Treatment in Dogs

Erik Portelius, Bianca Van Broeck, Ulf Andréasson et al. · Journal of Alzheimer s Disease · 2010 · 64 citations