Jacquie Maignel

Synthesis, Structure−Activity Relationships, and Pharmacological Profile of 9-Amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6,7,1-<i>h</i><i>i</i>]indoles:  Discovery of Potent, Selective Phosphodiesterase Type 4 Inhibitors

Catherine Burnouf, Eric Auclair, Nadine Avenel et al. · Journal of Medicinal Chemistry · 2000 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models

Mark Elliott, Christine Favre‐Guilmard, Sai Liu et al. · Science Advances · 2019 · 42 citations · Full text

Engineering, Neurology, Neuroscience +13

Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons

Nicole Yang, Jörg Isensee, Dylan V. Neel et al. · Nature Neuroscience · 2021 · 37 citations · Full text

Life Sciences, Neuroscience, Pharmacology +14

Augmentation of VAMP-catalytic activity of botulinum neurotoxin serotype B does not result in increased potency in physiological systems

Mark Elliott, Jacquie Maignel, Sai Liu et al. · PLoS ONE · 2017 · 12 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Botulinum Neurotoxins Serotypes A and B induce paralysis of mouse striated and smooth muscles with different potencies

Jacquie Maignel, Marion Huchet, Johannes Krupp · Pharmacology Research & Perspectives · 2017 · 11 citations · Full text

Medicine, Pharmacology, Physiology +15