Keith R. Hornberger - Concepedia

Author

Keith R. Hornberger

GlaxoSmithKline (United States)ORCID

Also Known As

K. Hornberger, K.R. Hornberger, Keith Hornberger, Keith R Hornberger, Keith R. Hornberger

Publications

1.6K

Citations

H-Index

Concepts

All Affiliations

GlaxoSmithKline (United States)Research Triangle Park Foundation Columbia University South College

About

Keith R. Hornberger is an author at GlaxoSmithKline (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	665
2	Biochemistry	6	6	317
3	Natural Sciences	5	5	353
4	Engineering	3	3	246
5	Health Sciences	1	1	121

Keith R. Hornberger

Publications

1.1K

Citations

H-Index

Page 1

	Year	Citations
Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors Tara Rheault, John Stellwagen, George M. Adjabeng, ACS Medicinal Chemistry Letters B-raf-driven TumorsAntitumor ActivityHyperactive SignalingTumor BiologyMedicinal Chemistry	2013	253
Total Synthesis of Leucascandrolide A Keith R. Hornberger, Christopher L. Hamblett, James L. Leighton Journal of the American Chemical Society Molecular SciencesBioorganic ChemistryEngineeringChemical MeasurementChemical Analysis	2000	185
Physicochemical Property Determinants of Oral Absorption for PROTAC Protein Degraders Keith R. Hornberger, Erika Araujo Journal of Medicinal Chemistry Protac Protein DegradersProtein RefoldingFood ChemistryPharmacological StudyProtein Folding	2023	121
Evidence for Allosteric Interactions of Antagonist Binding to the Smoothened Receptor Cynthia M. Rominger, Weilin Tiger Bee, Robert A. Copeland, Journal of Pharmacology and Experimental Therapeutics	2009	63
Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding Kyle A. Emmitte, George M. Adjebang, C. Webb Andrews, Bioorganic & Medicinal Chemistry Letters BiochemistryMedicineNatural SciencesReceptor Tyrosine KinaseProtein Phosphorylation	2009	61
Abstract B88: A selective Raf kinase inhibitor induces cell death and tumor regression of human cancer cell lines encoding B-RafV600E mutation Sylvie Laquerre, Marc R. Arnone, Katherine G. Moss, Molecular Cancer Therapeutics Tumor RegressionB-rafv600e MutationCell DeathSelectivity Towards B-rafCancer Biology	2009	54
Room-Temperature Pd-Catalyzed Amidation of Aryl Bromides Using <i>tert-</i>Butyl Carbamate Swapna Bhagwanth, Alex G. Waterson, George M. Adjabeng, The Journal of Organic Chemistry	2009	46
Synthetic Utility of Yeast Hexokinase. Substrate Specificity, Cofactor Regeneration, and Product Isolation H. Keith Chenault, Robert F. Mandes, Keith R. Hornberger The Journal of Organic Chemistry EngineeringEc 2.7.1.1Molecular BiologyFuranose AnalogsEnzymatic Modification	1997	42
A mild, one-pot synthesis of disubstituted benzimidazoles from 2-nitroanilines Keith R. Hornberger, George M. Adjabeng, Hamilton D. Dickson, Tetrahedron Letters Organic ChemistryCombinatorial ChemistryDisubstituted BenzimidazolesChemistry	2006	40
Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors Alex G. Waterson, Kimberly G. Petrov, Keith R. Hornberger, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryMedicinal ChemistryAniline HeadgroupsBiochemistryMedicine	2009	39

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