Zhe‐Ming Wu

Continuous production of aprepitant chiral intermediate by immobilized amidase in a packed bed bioreactor

Chao-Ping Lin, Zhe‐Ming Wu, Xiaoling Tang et al. · Bioresource Technology · 2018 · 35 citations

Packed Bed Bioreactor, Biomanufacturing, Engineering +9

Structure-Oriented Engineering of Amidase: Modification of Twisted Access Tunnel for Efficient Synthesis of 2-Chloronicotinic Acid

Zhe‐Ming Wu, Feng Xie, Wen Zheng et al. · ACS Catalysis · 2023 · 28 citations

Combinatorial Chemistry, Bioorganic Chemistry, Engineering +17

Highly regio- and enantioselective synthesis of chiral intermediate for pregabalin using one-pot bienzymatic cascade of nitrilase and amidase

Qin Zhang, Zhe‐Ming Wu, Chang-Ling Hao et al. · Applied Microbiology and Biotechnology · 2019 · 23 citations

Biosynthesis, Biochemistry, Chiral Intermediate +7

Efficient Chemoenzymatic Synthesis of Optically Active Pregabalin from Racemic Isobutylsuccinonitrile

Qin Zhang, Zhe‐Ming Wu, Shuang Liu et al. · Organic Process Research & Development · 2019 · 23 citations

Bioorganic Chemistry, Engineering, Organic Chemistry +18

Thermophilic esterase from Thermomyces lanuginosus: Molecular cloning, functional expression and biochemical characterization

Xiaojun Li, Ren‐Chao Zheng, Zhe‐Ming Wu et al. · Protein Expression and Purification · 2014 · 22 citations

Thermomyces Lanuginosus, Biosynthesis, Engineering +11