Qiuju Xun

Discovery of JND3229 as a New EGFR^C797S Mutant Inhibitor with In Vivo Monodrug Efficacy

Xiaoyun Lu, Tao Zhang, Sujie Zhu et al. · ACS Medicinal Chemistry Letters · 2018 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +11

Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors

Zhen Wang, Yali Zhang, Sergio G. Bartual et al. · ACS Medicinal Chemistry Letters · 2017 · 37 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2-<i>a</i>]pyrazin-3-ylethynyl)-4-isopropyl-<i>N</i>-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2

Zhen Wang, Yali Zhang, Daniel M. Pinkas et al. · Journal of Medicinal Chemistry · 2018 · 31 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Design, Synthesis, and Structure–Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-<i>d</i>]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors

Qiuju Xun, Zhang Zhang, Jinfeng Luo et al. · Journal of Medicinal Chemistry · 2018 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant

Xianglong Hu, Qiuju Xun, Tao Zhang et al. · Chinese Chemical Letters · 2019 · 19 citations

Pharmacy, Medicinal Chemistry, Oncology +11