Michaël Doré

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Matthew J. LaMarche, Michael Acker, Andreea Argintaru et al. · Journal of Medicinal Chemistry · 2020 · 207 citations · Full text

Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

Jeffrey T. Bagdanoff, Zhouliang Chen, Michael Acker et al. · Journal of Medicinal Chemistry · 2019 · 79 citations · Full text

Medicinal Chemistry, Signaling Pathway, Receptor Tyrosine Kinase +16

The Role of the Acidity of N-Heteroaryl Sulfonamides as Inhibitors of Bcl-2 Family Protein–Protein Interactions

B. Barry Touré, Karen Miller‐Moslin, Naeem Yusuff et al. · ACS Medicinal Chemistry Letters · 2013 · 72 citations · Full text

Combinatorial Chemistry, Antiapoptotic Members, Heterocycle Chemistry +16

Constitutive nitric oxide synthase activation is a significant route for nitroglycerin-mediated vasodilation

Marcelo G. Bonini, Krisztián Stadler, Sueli de Oliveira Silva et al. · Proceedings of the National Academy of Sciences · 2008 · 45 citations · Full text

Identification of a PPARδ agonist with partial agonistic activity on PPARγ

Richard Connors, Zhulun Wang, Martin Harrison et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 41 citations · Full text

Molecular Pharmacology, Medicine, Physiology +6