Jarrod A. Smith

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

M. Schulte, Allie Fu, Ping Zhao et al. · Nature Medicine · 2018 · 470 citations · Full text

Tumor Biology, Drug Targeting, Preclinical Models +10

Structure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel

CongBao Kang, Changlin Tian, Frank D. Sönnichsen et al. · Biochemistry · 2008 · 198 citations · Full text

The structure of calcyclin reveals a novel homodimeric fold for S100 Ca2+-binding proteins

Barbara C. M. Potts, Jarrod A. Smith, Mikael Akke et al. · Nature Structural & Molecular Biology · 1995 · 175 citations

Protein Function, Biochemistry, Protein Assembly +9

The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 PikC from Streptomyces venezuelae

David H. Sherman, Shengying Li, Liudmila V. Yermalitskaya et al. · Journal of Biological Chemistry · 2006 · 146 citations · Full text

On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation

Benjamin P. Brown, Yunkai Zhang, David Westover et al. · Clinical Cancer Research · 2019 · 107 citations · Full text