Jonathan D. Mortison

Targeting Xist with compounds that disrupt RNA structure and X inactivation

Rodrigo Aguilar, Kerrie B. Spencer, Barry Kesner et al. · Nature · 2022 · 125 citations · Full text

X Inactivation, Engineering, Natural Sciences +7

Biocatalytic Synthesis of Pikromycin, Methymycin, Neomethymycin, Novamethymycin, and Ketomethymycin

Douglas A. Hansen, Christopher M. Rath, Eli B. Eisman et al. · Journal of the American Chemical Society · 2013 · 67 citations · Full text

Biocatalytic Synthesis, Combinatorial Chemistry, Medicinal Chemistry +13

Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures

Jonathan D. Mortison, Monica Schenone, Jacob A. Myers et al. · Cell chemical biology · 2018 · 56 citations · Full text

Clinical Translation, Drug Discovery, Molecular Biology +4

A mass spectrometry-based proteome map of drug action in lung cancer cell lines

Benjamin Ruprecht, Julie Di Bernardo, Zhao Wang et al. · Nature Chemical Biology · 2020 · 53 citations

Proteomic Technology, Biochemistry, Tumor Microenvironment +12

Synthesis and Biochemical Analysis of Complex Chain-Elongation Intermediates for Interrogation of Molecular Specificity in the Erythromycin and Pikromycin Polyketide Synthases

Jonathan D. Mortison, Jeffrey D. Kittendorf, David H. Sherman · Journal of the American Chemical Society · 2009 · 33 citations · Full text

Engineering, Molecular Specificity, Molecular Biology +18