Rodrigo Aguilar

Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice

Fernando J. Bustos, Estíbaliz Ampuero, Nur Jury et al. · Brain · 2017 · 216 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Targeting Xist with compounds that disrupt RNA structure and X inactivation

Rodrigo Aguilar, Kerrie B. Spencer, Barry Kesner et al. · Nature · 2022 · 129 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +10

Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space

Noreen F. Rizvi, John P. Santa Maria, Ali Nahvi et al. · SLAS DISCOVERY · 2019 · 112 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +17

Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons

Cristián Arredondo, Carolina Cefaliello, Agnieszka Dyrda et al. · Neuron · 2022 · 87 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops

Hyun Jung Oh, Rodrigo Aguilar, Barry Kesner et al. · Cell · 2021 · 83 citations · Full text

Life Sciences, Genetics, Molecular Biology +16