Rodrigo Aguilar

Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice

Fernando J. Bustos, Estíbaliz Ampuero, Nur Jury et al. · Brain · 2017 · 211 citations · Full text

Epigenetic Change, Genetics, Epigenetics +20

Targeting Xist with compounds that disrupt RNA structure and X inactivation

Rodrigo Aguilar, Kerrie B. Spencer, Barry Kesner et al. · Nature · 2022 · 125 citations · Full text

X Inactivation, Engineering, Natural Sciences +7

Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space

Noreen F. Rizvi, John P. Santa Maria, Ali Nahvi et al. · SLAS DISCOVERY · 2019 · 102 citations · Full text

Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops

Hyun Jung Oh, Rodrigo Aguilar, Barry Kesner et al. · Cell · 2021 · 80 citations · Full text

Jpx Rna, Chromatin, Genetics +9

Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons

Cristián Arredondo, Carolina Cefaliello, Agnieszka Dyrda et al. · Neuron · 2022 · 79 citations · Full text

Excessive Release, Amyotrophic Lateral Sclerosis, Neurophysiology +10