Darian M. Bartkowski

Effects of p38 MAPK Inhibition on Early Stages of Diabetic Retinopathy and Sensory Nerve Function

Yunpeng Du, Jie Tang, Guanyuan Li et al. · Investigative Ophthalmology & Visual Science · 2010 · 135 citations · Full text

Medicine, Ophthalmology, Pharmacology +14

Effective Targeting of Hedgehog Signaling in a Medulloblastoma Model with PF-5274857, a Potent and Selective Smoothened Antagonist That Penetrates the Blood–Brain Barrier

Allison Rohner, Mary E. Spilker, Justine L. Lam et al. · Molecular Cancer Therapeutics · 2011 · 51 citations

Medicine, Oncology, Pharmacology +17

Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase

Frank Ruebsam, Douglas E. Murphy, Chinh Van Tran et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 43 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease

Nicola Brice, Hans H. Schiffer, Holger Monenschein et al. · Journal of Pharmacology and Experimental Therapeutics · 2021 · 43 citations

Medicine, Neuroscience, Pharmacology +17

Discovery of ANA975: An Oral Prodrug of the TLR-7 Agonist Isatoribine

Alan X. Xiang, Stephen E. Webber, Bradley M. Kerr et al. · Nucleosides Nucleotides & Nucleic Acids · 2007 · 38 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15