Lee W. Page

Discovery and structure–activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor

Muna Abdi, Paul Beswick, Andy Billinton et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 70 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +10

Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors

Christopher W. Murray, Valério Berdini, Ildiko M. Buck et al. · ACS Medicinal Chemistry Letters · 2015 · 60 citations · Full text

Medicinal Chemistry, Back Pocket, Drug Target +14

The intramolecular amination of allenes

George C. Feast, Lee W. Page, Jeremy Robertson · Chemical Communications · 2010 · 55 citations

Engineering, Heterocyclic, Biochemistry +13

A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 <i>H</i> ,2 <i>H</i> ,3 <i>H</i> -pyrrolo[3,2- <i>b</i> ]pyridin-1-yl)-2-[(2 <i>R</i> ,5 <i>R</i> )-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660)

Christopher N. Johnson, Jong Sook Ahn, Ildiko M. Buck et al. · Journal of Medicinal Chemistry · 2018 · 51 citations · Full text

Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain

Robert J. Gleave, Paul Beswick, Andrew J. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 44 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Anti-inflammatory +14