Edward McDonald - Concepedia

Author

Edward McDonald

Also Known As

B. Edward Mcdonald, E McDonald, E. MCDONALD, E. McDonald, E. Mcdonald, EDWARD MCDONALD, Edward A. McDonald, Edward D. McDonald, Edward McDonald, Edward Mcdonald

379

Publications

6.2K

Citations

H-Index

105

Concepts

All Affiliations

Institute of Cancer Research Cancer Research UK University of Cambridge

About

Edward McDonald is an author at Institute of Cancer Research specializing in natural sciences, biochemistry, and engineering.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Engineering	21	43	1.1K
2	Medicine	20	29	1.4K
3	Health Sciences	3	3	258
4	Language Studies	2	2	21
5	Arts	1	1	11

Edward McDonald

109

Publications

5.4K

Citations

H-Index

Page 1

	Year	Citations
NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Cancer Research	2008	469
4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer Paul A. Brough, Wynne Aherne, Xavier Barril, Journal of Medicinal Chemistry	2007	442
Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941 Florence I. Raynaud, Suzanne A. Eccles, Sonal Patel, Molecular Cancer Therapeutics	2009	270
Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design Brian Dymock, Xavier Barril, Paul A. Brough, Journal of Medicinal Chemistry Crystal StructureDrug TargetMolecular BiologyChemical BiologyMedicinal Chemistry	2005	231
Biosynthesis of the pigments of life: formation of the macrocycle Alan R. Battersby, Christopher J. R. Fookes, George W. J. Matcham, Nature BiologyBiosynthesisNatural PigmentsBiotransformationBiochemistry	1980	230
Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity Lindsay Stimson, Martin Rowlands, Yvette Newbatt, Molecular Cancer Therapeutics	2005	221
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors Kwai-Ming J. Cheung, Thomas P. Matthews, Karen James, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryDrug TargetBiochemistryHsp90 InhibitorsNatural Sciences	2005	219
Identification of Novel Small Molecule Inhibitors of Hypoxia-Inducible Factor-1 That Differentially Block Hypoxia-Inducible Factor-1 Activity and Hypoxia-Inducible Factor-1α Induction in Response to Hypoxic Stress and Growth Factors Noan‐Minh Chau, Paul Rogers, Wynne Aherne, Cancer Research	2005	146
Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall, Molecular Cancer Therapeutics	2007	142
Mechanism-Based Screen for G1/S Checkpoint Activators Identifies a Selective Activator of EIF2AK3/PERK Signalling Simon R. Stockwell, Georgina Platt, S. Elaine Barrie, PLoS ONE Reverse GeneticsMolecular RegulationMolecular BiologyCancer BiologyTumor Biology	2012	112

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