Lieve Umans

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

An Herreman, Dieter Hartmann, Wim Annaert et al. · Proceedings of the National Academy of Sciences · 1999 · 521 citations

Life Sciences, Genetics, Molecular Genetics +10

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin

Anton Roebroek, Lieve Umans, Ilse G.L. Pauli et al. · Development · 1998 · 302 citations · Full text

Life Sciences, Anatomy, Developmental Biology +17

Neuronal Deficiency of Presenilin 1 Inhibits Amyloid Plaque Formation and Corrects Hippocampal Long-Term Potentiation But Not a Cognitive Defect of Amyloid Precursor Protein [V717I] Transgenic Mice

Ilse Dewachter, Delphine Reversé, Nathalie Caluwaerts et al. · Journal of Neuroscience · 2002 · 238 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

Iván M. Moya, Lieve Umans, Elke Maas et al. · Developmental Cell · 2012 · 224 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Conditional Deletion of <i>Smad1</i> and <i>Smad5</i> in Somatic Cells of Male and Female Gonads Leads to Metastatic Tumor Development in Mice

Stephanie A. Pangas, Xiaohui Li, Lieve Umans et al. · Molecular and Cellular Biology · 2007 · 210 citations · Full text

Medicine, Developmental Biology, Genetics +16