Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

An Herreman, Dieter Hartmann, Wim Annaert, +14

Proceedings of the National Academy of Sciences

Total inactivation of γ–secretase activity in presenilin-deficient embryonic stem cells

An Herreman, Lutgarde Serneels, Wim Annaert, +3

Nature Cell Biology

Embryonic Stem CellDevelopmental BiologyMedicineNatural SciencesNeural Stem Cell +8

γ-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation

An Herreman, Geert Van Gassen, Mustapha Bentahir, +5

Journal of Cell Science

Role of Presenilins in Neuronal Calcium Homeostasis

Hua Zhang, Suxia Sun, An Herreman, +2

Journal of Neuroscience

Gene Expression Profiling Reveals Clear Differences Between EBV-Positive and EBV-Negative Posttransplant Lymphoproliferative Disorders

Julie Morscio, Daan Dierickx, José Luis Ferreiro, +9

American Journal of Transplantation

Lymphoid NeoplasiaImmunogeneticsTransplantationMedicineImmunology +8

Notch Is a Critical Component of the Mouse Somitogenesis Oscillator and Is Essential for the Formation of the Somites

Zoltán Ferjentsik, Shinichi Hayashi, J. Kim Dale, +6

PLoS Genetics

Molecular OscillatorCellular PhysiologyEmbryologyMouse Somitogenesis OscillatorCritical Component +15

Presenilins Mutated at Asp-257 or Asp-385 Restore Pen-2 Expression and Nicastrin Glycosylation but Remain Catalytically Inactive in the Absence of Wild Type Presenilin

Omar Nyabi, Mostafa Bentahir, Katrien Horré, +7

Journal of Biological Chemistry

Deficiency of Aph1B/C-γ-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment

Tim Dejaegere, Lutgarde Serneels, Martin Schäfer, +10

Proceedings of the National Academy of Sciences

The accuracy of positron emission tomography in the detection of posttransplant lymphoproliferative disorder

Daan Dierickx, Thomas Tousseyn, Annelies Requilé, +14

Haematologica

Notch pathway is dispensable for adipocyte specification

Amy M. Nichols, Yonghua Pan, An Herreman, +4

genesis

Metabolic RemodelingAdipokinesCellular PhysiologyInsulin SignalingObesity +16