Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity

Suzanne J. F. Kaptein, Sofie Jacobs, Lana Langendries, +32

Proceedings of the National Academy of Sciences

Antiviral CompoundEmerging Infectious DiseasesLacks ActivityHigh DoseMedicine +12

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

Iván M. Moya, Lieve Umans, Elke Maas, +8

Developmental Cell

Cell LineageSignal TransductionMolecular PhysiologyDevelopmental BiologySignaling Pathway +9

Cell Line Dependent RNA Expression Profiles of Prion-infected Mouse Neuronal Cells

Alex D. Greenwood, Marion Horsch, Anna Stengel, +8

Journal of Molecular Biology

Systems BiologyMolecular NeuroscienceEngineeringRna BiologyPrion Disease +3

Scrapie Infection of Prion Protein-deficient Cell Line upon Ectopic Expression of Mutant Prion Proteins

Elke Maas, Markus Geissen, Martin H. Groschup, +4

Journal of Biological Chemistry

GeneticsMolecular BiologyMutant PrpScrapie InfectionMouse Prp +16

Charged bipolar suramin derivatives induce aggregation of the prion protein at the cell surface and inhibit PrPSc replication

Max Nunziante, Claudia Kehler, Elke Maas, +3

Journal of Cell Science

Protein AssemblyMolecular BiologyCell CultureChemical BiologyPrion Replication +17

Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion

Paulo N. G. Pereira, Mariya P. Dobreva, Elke Maas, +8

Development

SclerostinMouse AmnionPrimitive StreakNodal SignalingEmbryology +15

Antiviral treatment of SARS-CoV-2-infected hamsters reveals a weak effect of favipiravir and a complete lack of effect for hydroxychloroquine

Suzanne J. F. Kaptein, Sofie Jacobs, Lana Langendries, +25

Antiviral TreatmentWeak EffectEmerging Infectious DiseasesMedicineViral Diagnostics +13

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells

Maria Gomes Fernandes, Ruben Dries, Matthias S. Roost, +15

Stem Cell Reports

Ultra-sensitive detection of prion protein fibrils by flow cytometry in blood from cattle affected with bovine spongiform encephalopathy

Lothar Trieschmann, Alexander Navarrete Santos, Katja Kaschig, +4

BMC Biotechnology

BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks

Karen Beets, Michael W. Staring, Nathan Criem, +5

BMC Developmental Biology