Alexandr A. Kapralov

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu et al. · Nature Chemical Biology · 2016 · 2.7K citations · Full text

Adrenal Gland, Oxysterol, Biochemistry +9

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

Valerian E. Kagan, Vladimir A. Tyurin, Jianfei Jiang et al. · Nature Chemical Biology · 2005 · 1.2K citations

Redox Signaling, Biochemistry, Natural Sciences +12

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

Charleen T. Chu, Jing Ji, Ruben K. Dagda et al. · Nature Cell Biology · 2013 · 1K citations · Full text

Mitophagy, Mitochondrial Function, Biochemistry +10

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals

Sally E. Wenzel, Yulia Y. Tyurina, Jinming Zhao et al. · Cell · 2017 · 891 citations · Full text

Oxysterol, Lipid Synthesis, Biochemistry +11

Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death

Alexandr A. Kapralov, Qin Yang, Haider H. Dar et al. · Nature Chemical Biology · 2020 · 589 citations · Full text

Inflammation, Commands Susceptibility, Redox Regulator +11