Joel M. Esken

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases

Timothy J. Miles, Alan J. Hennessy, B.D. Bax et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 63 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Medicine +13

Intramolecular Chiral Relay at Stereogenic Nitrogen. Synthesis and Application of a New Chiral Auxiliary Derived from (1<i>R</i>,2<i>S</i>)-Norephedrine and Acetone

Shawn R. Hitchcock, David M. Casper, Jeremy F. Vaughn et al. · The Journal of Organic Chemistry · 2004 · 53 citations

Toward the Development of a Structurally Novel Class of Chiral Auxiliaries:  Diastereoselective Aldol Reactions of a (1<i>R</i>,2<i>S</i>)-Ephedrine-Based 3,4,5,6-Tetrahydro-2<i>H</i>-1,3,4-oxadiazin-2-one

David M. Casper, James R. Burgeson, Joel M. Esken et al. · Organic Letters · 2002 · 52 citations

Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases

Timothy J. Miles, Alan J. Hennessy, B.D. Bax et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 46 citations · Full text

Novel Tricyclics, Inhibitory Activity, Medicinal Chemistry +12

Conformational Studies of <i>N</i>₃-Substituted [1,3,4]-Oxadiazinan-2-ones

David M. Casper, Jennifer R. Blackburn, Christopher D. Maroules et al. · The Journal of Organic Chemistry · 2002 · 26 citations