Filomena De Luca

Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

Bin Liu, Robert E. Lee Trout, Guo‐Hua Chu et al. · Journal of Medicinal Chemistry · 2019 · 281 citations · Full text

Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-Lactamases

Sushmita D. Lahiri, Stefano Mangani, Thomas F. Durand-Réville et al. · Antimicrobial Agents and Chemotherapy · 2013 · 217 citations · Full text

VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in <i>Enterobacterales</i> and Pseudomonas aeruginosa

Jodie C. Hamrick, Jean‐Denis Docquier, Tsuyoshi Uehara et al. · Antimicrobial Agents and Chemotherapy · 2019 · 204 citations · Full text

Crystal Structure of the OXA-48 β-Lactamase Reveals Mechanistic Diversity among Class D Carbapenemases

Jean‐Denis Docquier, V. Calderone, Filomena De Luca et al. · Chemistry & Biology · 2009 · 166 citations

Crystal Structure, Biochemistry, Class D Carbapenemases +7

CTX-M-Type Extended-Spectrum β-Lactamases in Italy: Molecular Epidemiology of an Emerging Countrywide Problem

C. Mugnaioli, Francesco Luzzaro, Filomena De Luca et al. · Antimicrobial Agents and Chemotherapy · 2006 · 122 citations · Full text

Molecular Epidemiology, Klebsiella Pneumoniae, Escherichia Coli +17