Paul R. McGuirk - Concepedia

Concepedia

Author

Paul R. McGuirk

Pfizer (United States)

Also Known As

P R McGuirk, P. R. MCGUIRK, P. R. McGuirk, P.R. McGuirk, PAUL R. MCGUIRK, Paul McGuirk, Paul R McGuirk, Paul R. McGuirk

48

Publications

1.4K

Citations

22

H-Index

65

Concepts

All Affiliations

Pfizer (United States)Vanderbilt University Aeromics (United States)

PR

About

Paul R. McGuirk is an author at Pfizer (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	871
2	Natural Sciences	8	8	669
3	Biochemistry	7	7	422
4	Engineering	4	4	187
5	Health Sciences	2	2	67

Paul R. McGuirk

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24

Publications

1.4K

Citations

22

H-Index

	Year	Citations
DNA knots reveal a chiral organization of DNA in phage capsids Javier Arsuaga, Mariel Vázquez, Paul R. McGuirk, Proceedings of the National Academy of Sciences DnaGeneticsIcosahedral BacteriophagesDna AnalysisMolecular Biology	2005	246
Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz, Journal of Biological Chemistry Medicinal ChemistryBiochemistryEnzyme-mediated Dna CleavageTopoisomerase IiNatural Sciences	1991	145
Highly stereoselective synthesis of trisubstituted olefins via addition of alkylcopper complexes to acetylenes Anthony Marfat, Paul R. McGuirk, Paul Helquist The Journal of Organic Chemistry EngineeringAlkene MetathesisTrisubstituted OlefinsAltmetric Attention ScoreOrganic Chemistry	1979	111
Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents John F. Barrett, Thomas D. Gootz, Paul R. McGuirk, Antimicrobial Agents and Chemotherapy Antiparasitic AgentImmunologyVitro Topoisomerase IiAntimicrobial ChemotherapyDna Cleavage	1989	93
Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz, Antimicrobial Agents and Chemotherapy Bioorganic ChemistryMolecular BiologyOrganic ChemistryChemical BiologyPharmaceutical Chemistry	1992	93
New Quinolone Compounds from Pseudonocardia sp. with Selective and Potent Anti-Helicobacter pylori Activity: Taxonomy of Producing Strain, Fermentation, Isolation, Structural Elucidation and Biological Activities. Koen Dekker, TAISUKE INAGAKI, Thomas D. Gootz, The Journal of Antibiotics	1998	68
Drug features that contribute to the activity of quinolones against mammalian topoisomerase II and cultured cells: correlation between enhancement of enzyme-mediated DNA cleavage in vitro and cytotoxic potential Sarah H. Elsea, Paul R. McGuirk, Thomas D. Gootz, Antimicrobial Agents and Chemotherapy Type Ii EnzymeMedicinal ChemistryBiochemistryEnzyme-mediated Dna CleavageTopoisomerase Ii	1993	64
Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury George W. Farr, Christopher Hall, Susan M. Farr, Neuroscience MedicineImproving OutcomeCns InjuryNeuropharmacologyBrain Injury	2019	62
Synthesis and structure-activity relationships of 7-diazabicycloalkylquinolones, including danofloxacin, a new quinolone antibacterial agent for veterinary medicine Paul R. McGuirk, Martin R. Jefson, Douglas Mann, Journal of Medicinal Chemistry	1992	47
Total synthesis of (+)-phyllanthocin Paul R. McGuirk, David B. Collum Journal of the American Chemical Society AltmetricsBioorganic ChemistryDonut IconNatural SciencesInformation	1982	42

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