Paul R. McGuirk

DNA knots reveal a chiral organization of DNA in phage capsids

Javier Arsuaga, Mariel Vázquez, Paul R. McGuirk et al. · Proceedings of the National Academy of Sciences · 2005 · 250 citations

Life Sciences, Biology, Microbiology +17

Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage

Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz et al. · Journal of Biological Chemistry · 1991 · 145 citations · Full text

Medicine, Molecular Biology, Pharmacology +15

Highly stereoselective synthesis of trisubstituted olefins via addition of alkylcopper complexes to acetylenes

Anthony Marfat, Paul R. McGuirk, Paul Helquist · The Journal of Organic Chemistry · 1979 · 111 citations

Natural Sciences, Chemistry, Organic Chemistry +8

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz et al. · Antimicrobial Agents and Chemotherapy · 1992 · 94 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents

John F. Barrett, Thomas D. Gootz, Paul R. McGuirk et al. · Antimicrobial Agents and Chemotherapy · 1989 · 93 citations

Medicine, Molecular Biology, Pharmacology +15