Paul R. McGuirk

DNA knots reveal a chiral organization of DNA in phage capsids

Javier Arsuaga, Mariel Vázquez, Paul R. McGuirk et al. · Proceedings of the National Academy of Sciences · 2005 · 246 citations

Dna, Genetics, Icosahedral Bacteriophages +19

Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage

Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz et al. · Journal of Biological Chemistry · 1991 · 145 citations · Full text

Medicinal Chemistry, Biochemistry, Enzyme-mediated Dna Cleavage +15

Highly stereoselective synthesis of trisubstituted olefins via addition of alkylcopper complexes to acetylenes

Anthony Marfat, Paul R. McGuirk, Paul Helquist · The Journal of Organic Chemistry · 1979 · 111 citations

Engineering, Alkene Metathesis, Trisubstituted Olefins +11

Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents

John F. Barrett, Thomas D. Gootz, Paul R. McGuirk et al. · Antimicrobial Agents and Chemotherapy · 1989 · 93 citations

Antiparasitic Agent, Immunology, Vitro Topoisomerase Ii +18

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz et al. · Antimicrobial Agents and Chemotherapy · 1992 · 93 citations · Full text

Bioorganic Chemistry, Molecular Biology, Organic Chemistry +18