Thomas D. Gootz

Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with an extended half-life and excellent tissue distribution

Agnès Girard, D Girard, A. R. English et al. · Antimicrobial Agents and Chemotherapy · 1987 · 323 citations

Medicine, Pharmacokinetics, Pharmacology +14

High-Level Carbapenem Resistance in a <i>Klebsiella pneumoniae</i> Clinical Isolate Is Due to the Combination of <i>bla</i> _ACT-1 β-Lactamase Production, Porin OmpK35/36 Insertional Inactivation, and Down-Regulation of the Phosphate Transport Porin PhoE

Frank M. Kaczmarek, Fadia B. Dib-Hajj, Wenchi Shang et al. · Antimicrobial Agents and Chemotherapy · 2006 · 240 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +16

Genetic Organization of Transposase Regions Surrounding <i>bla</i> _KPC Carbapenemase Genes on Plasmids from <i>Klebsiella</i> Strains Isolated in a New York City Hospital

Thomas D. Gootz, Mary Kay Lescoe, Fadia B. Dib-Hajj et al. · Antimicrobial Agents and Chemotherapy · 2009 · 155 citations · Full text

Life Sciences, Genetics, Microbiology +17

Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage

Megan J. Robinson, Barbara A. Martin, Thomas D. Gootz et al. · Journal of Biological Chemistry · 1991 · 145 citations · Full text

Medicine, Molecular Biology, Pharmacology +15

Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topoisomerase IV mutants of Streptococcus pneumoniae selected in vitro

Thomas D. Gootz, Richard P. Zaniewski, S L Haskell et al. · Antimicrobial Agents and Chemotherapy · 1996 · 137 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17