Paul Helquist

Structural insights into HDAC6 tubulin deacetylation and its selective inhibition

Y. Miyake, J.J. Keusch, Longlong Wang et al. · Nature Chemical Biology · 2016 · 297 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Synthesis with zerovalent nickel. Coupling of aryl halides with bis(1,5-cyclooctadiene)nickel(0)

M. F. SEMMELHACK, Paul Helquist, L. Jones · Journal of the American Chemical Society · 1971 · 243 citations

Natural Sciences, Chemistry, Inorganic Chemistry +9

Reaction of aryl and vinyl halides with zerovalent nickel - preparative aspects and the synthesis of alnusone

M. F. SEMMELHACK, Paul Helquist, L. Jones et al. · Journal of the American Chemical Society · 1981 · 223 citations

Natural Sciences, Chemistry, Inorganic Chemistry +5

Toward Selective Histone Deacetylase Inhibitor Design:  Homology Modeling, Docking Studies, and Molecular Dynamics Simulations of Human Class I Histone Deacetylases

Difei Wang, Paul Helquist, Norbert L. Wiech et al. · Journal of Medicinal Chemistry · 2005 · 211 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

Nina H. Pipalia, Casey C. Cosner, Amy Y. Huang et al. · Proceedings of the National Academy of Sciences · 2011 · 195 citations

Life Sciences, Biochemistry, Molecular Biology +17