Meire Bremer

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma

Henry R. Maun, Janet Jackman, David F. Choy et al. · Cell · 2019 · 106 citations · Full text

Asthma, Allergy, Allergy Medicine +7

IL-17A is associated with the breakdown of the blood-brain barrier in relapsing-remitting multiple sclerosis

A. Francesca Setiadi, Alexander R. Abbas, Surinder Jeet et al. · Journal of Neuroimmunology · 2019 · 88 citations · Full text

Neurological Disorder, Immunology, Immune Regulation +20

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis

Arna Katewa, Yugang Wang, Jason A. Hackney et al. · JCI Insight · 2017 · 72 citations · Full text

Potent and selective Bruton’s tyrosine kinase inhibitors: Discovery of GDC-0834

Wendy B. Young, J A Barbosa, Peter Blomgren et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 64 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +11

Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Volunteers Treated With GDC‐0853, a Selective Reversible Bruton's Tyrosine Kinase Inhibitor

Ann Herman, Leslie W. Chinn, Shweta G. Kotwal et al. · Clinical Pharmacology & Therapeutics · 2018 · 64 citations