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Potent and selective Bruton’s tyrosine kinase inhibitors: Discovery of GDC-0834

Wendy B. Young, J A Barbosa, Peter Blomgren, Meire Bremer, James J. Crawford, Donna M. Dambach, Steve Gallion, S.G. Hymowitz, Jeffrey E. Kropf, Seung‐Hwan Lee,

Bioorganic & Medicinal Chemistry Letters · 2015 · 64 citations · 12 references

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AGAMMAGLOBULINEMIA

Ogden C. Bruton · PEDIATRICS · 1952 · 1.4K citations

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Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis

Julie A. Di Paolo, Tao Huang, Mercedesz Balázs et al. · Nature Chemical Biology · 2010 · 328 citations · Full text

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The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective

Anne B. Satterthwaite, Owen N. Witte · Immunological Reviews · 2000 · 207 citations

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The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective

Anne B. Satterthwaite, Owen N. Witte · Immunological Reviews · 2000 · 197 citations

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Ability of the xid gene to prevent autoimmunity in (NZB X NZW)F1 mice during the course of their natural history, after polyclonal stimulation, or following immunization with DNA.

Bernhard Steinberg, P A Smathers, Katrine Hartmund Frederiksen et al. · Journal of Clinical Investigation · 1982 · 130 citations · Full text

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