Alfreda Beasley

Phosphorylation of phosphodiesterase‐5 by cyclic nucleotide‐dependent protein kinase alters its catalytic and allosteric cGMP‐binding activities

Jackie D. Corbin, Illarion V. Turko, Alfreda Beasley et al. · European Journal of Biochemistry · 2000 · 268 citations · Full text

High lung PDE5: A strong basis for treating pulmonary hypertension with PDE5 inhibitors

Jackie D. Corbin, Alfreda Beasley, Mitsi A. Blount et al. · Biochemical and Biophysical Research Communications · 2005 · 200 citations

Hypertension, Pulmonary Arterial Hypertension, Pulmonary Circulation +11

Binding of Tritiated Sildenafil, Tadalafil, or Vardenafil to the Phosphodiesterase-5 Catalytic Site Displays Potency, Specificity, Heterogeneity, and cGMP Stimulation

Mitsi A. Blount, Alfreda Beasley, Roya Zoraghi et al. · Molecular Pharmacology · 2004 · 174 citations

Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5)

Jackie D. Corbin, Alfreda Beasley, Mitsi A. Blount et al. · Neurochemistry International · 2004 · 87 citations

Molecular Pharmacology, Medicinal Chemistry, Higher Potency +6

[3H]Sildenafil Binding to Phosphodiesterase-5 Is Specific, Kinetically Heterogeneous, and Stimulated by cGMP

Jackie D. Corbin, Mitsi A. Blount, James L. Weeks et al. · Molecular Pharmacology · 2003 · 75 citations