Carmen Klein

Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion

Yan Lan, Mahmoud Moustafa, Maximilian Knoll et al. · Cancer Cell · 2021 · 178 citations · Full text

Overcoming hypoxia-induced tumor radioresistance in non-small cell lung cancer by targeting DNA-dependent protein kinase in combination with carbon ion irradiation

Carmen Klein, Andrea Mairani, Stewart Mein et al. · Radiation Oncology · 2017 · 105 citations · Full text

Assessment of RBE-Weighted Dose Models for Carbon Ion Therapy Toward Modernization of Clinical Practice at HIT: In Vitro, in Vivo, and in Patients

Stewart Mein, Carmen Klein, Benedikt Kopp et al. · International Journal of Radiation Oncology*Biology*Physics · 2020 · 67 citations

Preclinical Drug Evaluation, Rbe-weighted Dose Models, Pharmacotherapy +7

Biophysical modeling and experimental validation of relative biological effectiveness (RBE) for 4He ion beam therapy

Stewart Mein, Carmen Klein, Thomas Tessonnier et al. · Radiation Oncology · 2019 · 52 citations · Full text

Modeling the Effect of Hypoxia and DNA Repair Inhibition on Cell Survival after Photon Irradiation

Hans Liew, Carmen Klein, Frank T. Zenke et al. · International Journal of Molecular Sciences · 2019 · 18 citations · Full text

Dna Damage, Radiation Effect, Radiation Exposure +23