Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response

Jingwen Lin, Chao Tang, Han-cheng Wei, +71

Cell Host & Microbe

Viral PathogenesisImmunologyVirologyNsp1 Deletion VariantSars-cov-2 Uncovers +6

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model*

Michael L. Booker, Cecilia M. Bastos, Martin Kramer, +27

Journal of Biological Chemistry

A Novel ‘Gene Insertion/Marker Out’ (GIMO) Method for Transgene Expression and Gene Complementation in Rodent Malaria Parasites

Jingwen Lin, Takeshi Annoura, Mohammed Sajid, +6

PLoS ONE

EngineeringReverse GeneticsTransgene ExpressionGeneticsMalaria +17

Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer

Li Zhang, Yiming Zhang, Chengdi Wang, +22

Signal Transduction and Targeted Therapy

Hemozoin Induces Lung Inflammation and Correlates with Malaria-Associated Acute Respiratory Distress Syndrome

Katrien Deroost, Ariane Tyberghein, Natacha Lays, +12

American Journal of Respiratory Cell and Molecular Biology

Acute Lung InjuryAsthmaInflammatory Lung DiseaseLung InflammationRespiratory Distress Syndrome (Pulmonary Critical Care) +15

Two <i>Plasmodium</i> 6‐Cys family‐related proteins have distinct and critical roles in liver‐stage development

Takeshi Annoura, Ben C. L. van Schaijk, Ivo Ploemen, +21

The FASEB Journal

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

Akul Singhania, Christine M. Graham, Leona Gabryšová, +31

Nature Communications

Replication of <i>Plasmodium</i> in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance

Jingwen Lin, Roberta Spaccapelo, Evelin Schwarzer, +21

The Journal of Experimental Medicine

MalariaImmunologyChloroquine ResistancePlasmodium Hb DegradationRedox Biology +16

Repeated clinical malaria episodes are associated with modification of the immune system in children

Yaw Bediako, Rhys Adams, Adam J. Reid, +21

BMC Medicine

Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection

Thibaut Brugat, Adam J. Reid, Jingwen Lin, +15

Nature Microbiology

MalariaImmunologyHumoral ResponseChronic Plasmodium InfectionAutoimmunity +1