Hiroko Koretsune

Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group

Tomomichi Chonan, Daisuke Wakasugi, Daisuke Yamamoto et al. · Bioorganic & Medicinal Chemistry · 2011 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

TP0463518, a Novel Prolyl Hydroxylase Inhibitor, Specifically Induces Erythropoietin Production in the Liver

Sota Kato, Nagahiro Ochiai, Hiroki Takano et al. · Journal of Pharmacology and Experimental Therapeutics · 2019 · 22 citations

Medicine, Biochemistry, Pharmacology +12

(4-Piperidinyl)-piperazine: A new platform for acetyl-CoA carboxylase inhibitors

Tomomichi Chonan, Takahiro Oi, Daisuke Yamamoto et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 21 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors

Tomomichi Chonan, Hiroki Tanaka, Daisuke Yamamoto et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

SGL5213, a novel and potent intestinal SGLT1 inhibitor, suppresses intestinal glucose absorption and enhances plasma GLP-1 and GLP-2 secretion in rats

Fusayo Io, Emi Gunji, Hiroko Koretsune et al. · European Journal of Pharmacology · 2019 · 13 citations

Medicine, Endocrinology, Pharmacology +15