Fusayo Io

(1<i>S</i>)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-<scp>d</scp>-glucitol (TS-071) is a Potent, Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for Type 2 Diabetes Treatment

Hiroyuki Kakinuma, Takahiro Oi, Yuko Hashimoto-Tsuchiya et al. · Journal of Medicinal Chemistry · 2010 · 158 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group

Tomomichi Chonan, Daisuke Wakasugi, Daisuke Yamamoto et al. · Bioorganic & Medicinal Chemistry · 2011 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains

Misato Kobayashi, Fusayo Io, Takahiro Kawai et al. · Diabetologia · 2006 · 28 citations · Full text

Life Sciences, Endocrinology, Genetics +11

Effects of SGLT2 inhibitors on the onset of esophageal varices and extrahepatic cancer in type 2 diabetic patients with suspected MASLD: a nationwide database study in Japan

Takumi Kawaguchi, Yoshiyuki Fujishima, Daisuke Wakasugi et al. · Journal of Gastroenterology · 2024 · 28 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

TP0463518, a Novel Prolyl Hydroxylase Inhibitor, Specifically Induces Erythropoietin Production in the Liver

Sota Kato, Nagahiro Ochiai, Hiroki Takano et al. · Journal of Pharmacology and Experimental Therapeutics · 2019 · 22 citations

Medicine, Biochemistry, Pharmacology +12