Daisuke Wakasugi

A versatile synthesis, including asymmetric synthesis, of bicyclo[n.1.0]alkanes from cyclic ketones via the magnesium carbenoid 1,3-CH insertion as a key reaction

Tsuyoshi Satoh, Shingo Ogata, Daisuke Wakasugi · Tetrahedron Letters · 2006 · 39 citations

Cross-coupling Reaction, Heterocyclic, Cyclic Ketones +5

Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group

Tomomichi Chonan, Daisuke Wakasugi, Daisuke Yamamoto et al. · Bioorganic & Medicinal Chemistry · 2011 · 33 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +9

A synthesis of bicyclo[n.1.0]alkanes having tert-butyl carboxylate or acetamide moiety via the intramolecular 1,3-CH insertion of magnesium carbenoids

Shingo Ogata, Hideki Saitoh, Daisuke Wakasugi et al. · Tetrahedron · 2008 · 24 citations

Heterocyclic, Natural Sciences, Diversity-oriented Synthesis +7

A novel synthesis, including asymmetric synthesis, of 2,4,4-trisubstituted 2-cyclopentenones based on the reaction of 1-chlorovinyl p-tolyl sulfoxides with acetonitrile and its homologues

Daisuke Wakasugi, Tsuyoshi Satoh · Tetrahedron · 2004 · 23 citations

Heterocyclic, 2,4,4-Trisubstituted 2-Cyclopentenones, Asymmetric Synthesis +6

(4-Piperidinyl)-piperazine: A new platform for acetyl-CoA carboxylase inhibitors

Tomomichi Chonan, Takahiro Oi, Daisuke Yamamoto et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 21 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +6