Petra Niessen

Overexpression of Glyoxalase-I Reduces Hyperglycemia-induced Levels of Advanced Glycation End Products and Oxidative Stress in Diabetic Rats

Olaf Brouwers, Petra Niessen, Isabel Ferreira et al. · Journal of Biological Chemistry · 2010 · 227 citations · Full text

Life Sciences, Biochemistry, Endocrinology +15

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

Olaf Brouwers, Petra Niessen, Guido R.M.M. Haenen et al. · Diabetologia · 2010 · 191 citations · Full text

Life Sciences, Biochemistry, Physiology +14

N ^ε -(Carboxymethyl)lysine-Receptor for Advanced Glycation End Product Axis Is a Key Modulator of Obesity-Induced Dysregulation of Adipokine Expression and Insulin Resistance

Katrien H.J. Gaens, Gijs H. Goossens, Petra Niessen et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2014 · 190 citations · Full text

Life Sciences, Endocrinology, Physiology +17

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes

Olaf Brouwers, Petra Niessen, Toshio Miyata et al. · Diabetologia · 2013 · 138 citations · Full text

Medicine, Nephrology, Physiology +14

Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis

Katrien H.J. Gaens, Petra Niessen, Sander S. Rensen et al. · Journal of Hepatology · 2011 · 105 citations · Full text

Life Sciences, Biochemistry, Cell Signaling +13