Daratumumab induces mechanisms of immune activation through CD38+ NK cell targeting

Domenico Viola, Ada Donà, Enrico Caserta, +25

Leukemia

InflammationCancer ImmunosurveillanceAutoimmune DiseaseImmune ActivationAllergy +12

Design of Potent pan-IAP and Lys-Covalent XIAP Selective Inhibitors Using a Thermodynamics Driven Approach

Carlo Baggio, Luca Gambini, Parima Udompholkul, +6

Journal of Medicinal Chemistry

Combinatorial ChemistryPharmaceutical ScienceChemistryChemical BiologyPharmaceutical Chemistry +16

Bergapten induces metabolic reprogramming in breast cancer cells

Marta Santoro, Carmela Guido, Francesca De Amicis, +6

Oncology Reports

MiR-16 regulates crosstalk in NF-κB tolerogenic inflammatory signaling between myeloma cells and bone marrow macrophages

Jihane Khalife, Jayeeta Ghose, Marianna Martella, +18

JCI Insight

FoxO3a as a Positive Prognostic Marker and a Therapeutic Target in Tamoxifen-Resistant Breast Cancer

Michele Pellegrino, Pietro Rizza, Ada Donà, +11

Cancers

Androgens downregulate miR-21 expression in breast cancer cells underlining the protective role of androgen receptor

Ivan Casaburi, Maria Grazia Cesario, Ada Donà, +10

Oncotarget

Androgen ReceptorMir-21 ExpressionBreast OncologyImmunologyEpigenetics +14

Ligand activated progesterone receptor B drives autophagy-senescence transition through a Beclin-1/Bcl-2 dependent mechanism in human breast cancer cells

Francesca De Amicis, Carmela Guido, Marta Santoro, +11

Oncotarget

Immune Mediated Mechanisms of Resistance to Daratumumab

Domenico Viola, Ada Donà, Emine Gulsen Gunes, +15

Blood

A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-γ–induced CD38 expression

Mariam Murtadha, Miso Park, Yinghui Zhu, +22

Blood

Oncolytic herpes simplex virus infects myeloma cells in vitro and in vivo

Jayeeta Ghose, Ada Donà, Mariam Murtadha, +15

Molecular Therapy — Oncolytics